URN Research Spotlights


This Research Spotlight Series showcases UVA students’ research. DM @uvaurn or email us to enter!

Impact of Volume Resuscitation for Severe Sepsis and Septic Shock on Development of ARDS and Hospital Mortality – Heidi Freking

I worked under Dr. Alexandra Kadl, a professor in the Department of Medicine. Aggressive volume fluid resuscitation is a standard treatment for severe sepsis and septic shock, but it is debated whether a conservative or liberal fluid management strategy is best for improving the outcome of patients. In a retrospective study, we sought to determine whether ventilator free days and hospital mortality correlated with the amount of volume administered at 24 and 72 hours after onset of severe sepsis or septic shock in patients transferred from the medical floor.